A Case of Alzheimer’s Disease Manifesting as Posterior Cortical Atrophy

J Korean Neurol Assoc > Volume 17(6); 1999 > Article

Journal of the Korean Neurological Association 1999;17(6): 886-890.

알쯔하이머병으로 확인된 Posterior Cortical Atrophy 1예

최성혜*, 나덕렬 ·하충건*·서연림**

성균관대학교 의과대학 삼성서울병원 신경과,진단병리과**,인하대학교 의과대학 신경과*

A Case of Alzheimer’s Disease Manifesting as Posterior Cortical Atrophy

Seong Hye Choi, M.D.*, Duk L. Na, M.D., Choong-Kun Ha, M.D.*, Yeon-Lim Suh, M.D.**

Department of Neurology and Pathology,** Samsung Medical Center, Sungkyunkwan University School of Medicine, Department of Neurology, College of Medicine, Inha University*

Abstract

A subgroup of patients with progressive degenerative dementia that begins with higher visual dysfunction has been referred to as posterior cortical atrophy (PCA). A 55-year-old woman presented with progressive visual disturbance for 4 years, which was followed by geographical disorientation, impairment of writing and calculation, and memory distur-bance. Neuropsychological deficits were characterized by Balint syndrome, visuospatial dysfunction, prosopagnosia, Gerstmann syndrome and apraxia. Brain MRI showed mild diffuse atrophy. F18-FDG-PET disclosed bilateral occipi-totemporoparietal hypometabolism, more pronounced on the right. Biopsy from right temporal lobe revealed neu-ropathological findings consistent with Alzheimer’s disease. J Korean Neurol Assoc 17(6):886~890, 1999 Key Words : Posterior cortical atrophy, Alzheimer’s disease, Dementia, Balint syndrome