Effect of Lorazepam injection on Status Epilepticus

J Korean Neurol Assoc > Volume 1(2); 1983 > Article

Journal of the Korean Neurological Association 1983;1(2): 10-16.

간질중첩증 환자에 대한 Lorazepam주사의 효과

서울대학교 신경과.

Effect of Lorazepam injection on Status Epilepticus

Ho-Jin Myong, M.D.

Department of Neurology, Seoul National University

Abstract

Status epilepticus is a neurological emergency requiring immediate effective care to avoid permanent brain damage or death. There is no single ideal pharmacological agent that can be used for status epilepticus. The author has studied the effect of intravenous lorazepam in the tratment of status epilepticus occurring in eighteen patients. Lorazepam controlled status epilepticus in sixteen (88%) of the eighteen patents, showed no side effect such as depressant action on respiratory and cardiovascular system. Also it seemed that lorazepam acted rapidly and its effect lasted at least for over eight hours. Except a few cases who had had prolonged hangover, the injection seemed to be handy and safe treatment without requiring EKG monitoring and repeated electrolyte check etc. as in dilantinization.